Author

Kyle M. Kovary

Stanford UniversityORCID 0000-0002-7616-2968Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Mary N. TerueliD· 2 shared Michael L. ZhaoiD· 2 shared Brooks E. Taylor· 1 shared Edward L. LaGoryiD· 1 shared Markus W. CovertiD· 1 shared Takamasa KudoiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 12 mutual co-author links

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2 shared papersSystems Biology

Mary N. TeruelORCID

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2 papers

Recent·Most cited

A dynamic HIF1alpha-PPARgamma circuit controls a paradoxical adipocyte regulatory landscape

Takamasa Kudo, Michael L. Zhao, Kyle M. Kovary, Edward L. LaGory, Markus W. Covert, Mary N. Teruel

The paper identifies a dynamic HIF1alpha-PPARgamma circuit that both promotes and represses lipid accumulation during adipogenesis, revealing a mechanism for adipocyte dysfunction in obesity.

bioRxiv · May 17, 2022 · PreprintSystems Biology

Expression variation and covariation impair analog and enable binary signaling control

Kyle M. Kovary, Brooks E. Taylor, Michael L. Zhao, Mary N. Teruel

The paper measures protein expression variability in Xenopus laevis and human cells, showing lower variation than expected and demonstrating how covariation between MEK and ERK improves population-level control of binary cell-fate decisions.

Molecular Systems Biology · May 1, 2018Peer-reviewedSystems Biology