Author

Nina H. Pipalia

Weill Cornell MedicineORCID 0000-0002-7619-7351Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Frederick R. MaxfieldiD· 2 shared Alison GoateiD· 1 shared Amy Y. Huang· 1 shared Bin ZhangiD· 1 shared David M. HoltzmaniD· 1 shared Edoardo M. MarcoraiD· 1 shared Elizabeth SikoraiD· 1 shared Harold Ralph· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Frederick R. MaxfieldORCID

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2 papers

Recent·Most cited

Screening of small molecule chemical library identifies leads that reduce cholesterol accumulation in human NPC1 fibroblasts

Nina H. Pipalia, Amy Y. Huang, Harold Ralph, Frederick R. Maxfield

The paper identifies small molecule compounds that reduce cholesterol accumulation in human NPC1 mutant fibroblasts but not in NPC1-/- cells, suggesting on-target effects.

bioRxiv · Nov 16, 2022 · PreprintNeuroscience

Cholesterol and matrisome pathways dysregulated in human APOE ε4 glia

Julia TCW, Shuang Liang, Qian Lü, Nina H. Pipalia, Michael J. Chao, Yang Shi, Sarah E. Bertelsen, Manav Kapoor, Edoardo M. Marcora, Elizabeth Sikora, David M. Holtzman, Frederick R. Maxfield, Bin Zhang, Minghui Wang, Wayne W. Poon, Alison Goate

This study identifies dysregulation of cholesterol and matrisome pathways in human APOE ε4 glia, linking them to Alzheimer's disease risk.

bioRxiv · Jul 25, 2019 · PreprintNeuroscience