Author

Samrat Das

Centre international de recherche sur le cancerORCID 0000-0002-7672-3374Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Cécilia Sirand· 2 shared Claire RenardiD· 2 shared François VirardiD· 2 shared Jiří ZavadiliD· 2 shared Michael KorenjakiD· 2 shared Stéphane Keïta· 2 shared Vincent CahaisiD· 2 shared Akram GhantousiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersGenomics

Cécilia Sirand

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2 papers

Recent·Most cited

Human cancer genomes harbor the mutational signature of tobacco-specific nitrosamines NNN and NNK

Michael Korenjak, Nuri A. Temiz, Stéphane Keïta, Bérénice Chavanel, Claire Renard, Cécilia Sirand, Vincent Cahais, Tanguy Mayel, Karin R. Vevang, Foster C. Jacobs, Jiehong Guo, William E. Smith, Marissa K. Oram, Flaviu Tăbăran, Ozan Ahlat, , Jiří Zavadil

The paper identifies mutational signatures in cancer genomes caused by tobacco-specific nitrosamines NNN and NNK, showing their unique contribution to specific cancer types.

Genome Medicine · Jul 2, 2026Peer-reviewedGenomics

Molecular and cell phenotype programs in oral epithelial cells directed by co-exposure to arsenic and smokeless tobacco

Samrat Das, Shefali Thakur, Vincent Cahais, François Virard, Liesel Claeys, Claire Renard, Cyrille Cuenin, Marie‐Pierre Cros, Stéphane Keïta, Assunta Venuti, Cécilia Sirand, Akram Ghantous, Zdenko Herceg, Michael Korenjak, Jiří Zavadil

This study investigates the molecular and cellular responses of oral epithelial cells to arsenic and smokeless tobacco exposure using multi-omics analysis and identifies key mechanisms linked to cancer progression.

BioFactors · Mar 1, 2025Peer-reviewedCancer Biology