Reza Shadmehr

The paper shows climbing fibers in the cerebellum encode the gradient of a loss function, solving the credit assignment problem by scaling error with reward prediction errors.

The paper investigates how electrical coupling among inhibitory neurons in the cerebellum coordinates spike timing to enhance temporal precision in downstream neurons.

This study investigates how goal uncertainty affects implicit sensorimotor adaptation and finds that it significantly reduces adaptation, independent of visual and kinematic factors.

The paper tests null space theory in marmoset cerebellum by showing Purkinje cell spikes cancel when perpendicular to movement, using spike-triggered averaging and population activity analysis.

This study investigates how Purkinje cells in the cerebellum control tongue movements in marmosets by suppressing their activity during specific phases of movement.

The paper investigates how the inferior olive informs Purkinje cells about sensory events and movement plans in marmosets, revealing two distinct groups with different spike patterns related to movement control.

The paper rejuvenates silicon probes by stripping and recoating their polymer coating, restoring signal quality after degradation from repeated use.

The paper develops a software tool for at-home sensorimotor adaptation studies, showing similar behavioral results to lab settings.

The paper investigates whether age-related reduction in movement vigor is due to decreased reward valuation or increased effort costs, finding that older adults expend more energy during reaching and show less reward sensitivity.

The paper shows that increased effort cost of harvest in marmosets leads to longer work duration, reduced movement vigor, and pupil constriction, suggesting a coordinated neural response to optimize fitness.

The paper shows that complex spikes in Purkinje cells alter saccadic eye movements by pulling them toward the visual space preferred by the olivary input to those cells.

This study investigates whether control of moving and holding is independently affected in stroke patients, finding functional separation between these modes of control despite shared characteristics in resting biases and movement synergies.

The paper evaluates how perturbation variance affects implicit error sensitivity in learning, finding that it reduces sensitivity while accounting for error size, contradicting an alternative view.

This study shows that cerebellar Purkinje cells use spike synchronization, not firing rates, to signal when to stop saccadic eye movements in marmosets.

The paper shows that saccade velocity during deliberation reflects the subjective value of effortful choices, even when the movement itself does not influence the decision.

The paper investigates how implicit and explicit learning systems compete during sensorimotor adaptation, showing that shared error signals can lead to competition and reduced learning in one system when the other is enhanced.

This study shows that correcting movement errors during sensorimotor adaptation carries an implicit cost, affecting learning efficiency based on error cost modulation.

P-sort is an open-source software that improves spike detection and attribution in cerebellar Purkinje cells by merging and splitting clusters based on statistical relationships between simple and complex spikes.

This study shows that reward history influences both decision-making duration and movement speed in foraging tasks.

This study shows that residual errors in motor adaptation are due to implicit learning's error sensitivity, which depends on past error history, not forgetting.

This paper reviews how cerebellar Purkinje cell populations function as surrogate teachers to guide learning in deep cerebellar nucleus neurons through error signals and complex spike synchrony.

The paper shows that saccade vigor correlates with subjective value of visual stimuli, but only partially predicts choice behavior.

The paper investigates spontaneous recovery of motor memory in humans by analyzing saccadic eye movements, identifying two distinct adaptive processes during different phases of movement.

This study investigates anterograde interference in visuomotor adaptation, finding two distinct mechanisms affecting performance over time.

The paper investigates how arm holding is controlled by showing that postural fields integrate reach commands, even after corticospinal damage.

The paper describes behavioral training and electrophysiological recording protocols in marmosets to increase trial numbers and target cerebellar Purkinje cells.

The paper tests if reward prediction error (RPE) modulates saccade vigor by inducing RPE events before saccade onset and measuring their effect on saccade velocity and reaction time.

The paper examines how a new editorial policy at Journal of Neuroscience affected rejection rates of human behavioral papers, finding a 30% decline in their proportion since 2015.