Author

Xiaolong Wu

East China University of Science and TechnologyORCID 0000-0002-7713-1995Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:graph neural network· 1

Frequent Co-Authors

Mingyue ZhengiD· 2 shared Dingyan WangiD· 1 shared Feisheng ZhongiD· 1 shared Hualiang JiangiD· 1 shared Kaixian CheniD· 1 shared Lehan Zhang· 1 shared Tianbiao Yang· 1 shared Xiaohong LiuiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

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10 top collaborators · 37 mutual co-author links

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2 shared papersBioinformatics

Mingyue ZhengORCID

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2 papers

Recent·Most cited

GDOP: A graph convolutional network-based drug "on-target" pathway prediction algorithm

Xiaolong Wu, Lehan Zhang, Mingyue Zheng

GDOP predicts drug 'on-target' pathways using graph convolutional networks, achieving high AUC-ROC and Top10 accuracy on LINCS data.

bioRxiv · Mar 3, 2024 · PreprintBioinformatics

Computational target fishing by mining transcriptional data using a novel Siamese spectral-based graph convolutional network

Feisheng Zhong, Xiaolong Wu, Xutong Li, Dingyan Wang, Zunyun Fu, Xiaohong Liu, Xiaozhe Wan, Tianbiao Yang, Xiaomin Luo, Kaixian Chen, Hualiang Jiang, Mingyue Zheng

The paper introduces a Siamese spectral-based graph convolutional network to infer protein targets of chemical compounds from gene expression data, achieving better performance than existing methods.

bioRxiv · Apr 1, 2020 · PreprintBioinformatics