Author

Eva‐Maria Mandelkow

Center of Advanced European Studies and ResearchORCID 0000-0002-7715-4038Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Eckhard Mandelkow�iD· 2 shared Jacek BiernatiD· 2 shared Senthilvelrajan KaniyappaniD· 2 shared Bettina WarscheidiD· 1 shared Christoph KlattiD· 1 shared Friedel DrepperiD· 1 shared Helmut E. MeyeriD· 1 shared Katharina Tepper· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Eckhard Mandelkow�ORCID

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2 papers

Recent·Most cited

NeuroscienceJournal of Biological ChemistryPeer-reviewedOct 26, 2020

Combinatorial native MS and LC-MS/MS approach reveals high intrinsic phosphorylation of human Tau but minimal levels of other key modifications

Friedel Drepper, Jacek Biernat, Senthilvelrajan Kaniyappan…·Eckhard Mandelkow�

54 citationstop 5%

humanproteomics

NeuroscienceMolecular NeurodegenerationPeer-reviewedJul 16, 2020

FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau fibers

Senthilvelrajan Kaniyappan, Katharina Tepper, Jacek Biernat…·Eckhard Mandelkow�

This paper shows that FRET-based Tau seeding assays do not reflect prion-like templated assembly of Tau fibers, as GFP tags inhibit aggregation and alter fiber structure.

64 citationstop 3%

protein structureexperimental assay