Friedel Drepper

This study reveals how mitochondrial complex III assembles from preformed matrix domain modules, showing dynamic subunit exchange and the role of specific residues in assembly and disease.

This study identifies two distinct core minor pilin complexes in cyanobacteria that prime specialized Type IV filaments for natural competence and motility.

The paper develops an ER retrieval-and-release system to study ligand-independent basal TCR signaling, finding that surface TCRs generate distinct phosphorylation patterns compared to ligand-induced activation.

This paper reports cryo-EM structures of EMO and EMO-ETF complex from Syntrophus aciditrophicus, revealing a twin-heme-mediated reverse redox-loop mechanism for methanogenesis from fatty acids.

This paper characterizes the function of the cyanobacterial gene ssr3189 by analyzing its deletion mutant, revealing its role in linking translation with metabolic control and RNA decay.

This study identifies a PP2A regulatory network in Sulfolobus acidocaldarius that controls surface structures and motility through phosphorylation-dependent signaling.

This study examines the growth, morphology, and surface appendages of Litorilinea aerophila, revealing unique features of its cell envelope and multicellular organization.

This study shows TAF2's intrinsically disordered region drives condensation in nuclear speckles, recruiting SRRM2 to TFIID and affecting alternative splicing.

This study identifies RNase J as a new enzyme involved in crRNA maturation in the type III-Bv CRISPR-Cas system of Synechocystis sp. PCC 6803, working with RNase E and possibly another RNase.

The paper identifies YqjD/ElaB/YgaM as ribosome-hibernating proteins that inhibit translation by blocking the ribosomal tunnel, similar to antimicrobial peptides and macrolide antibiotics.

Autoprot provides a Python module for proteomics data analysis, integrating R algorithms and interactive visualization for MS-based experiments processed with MaxQuant.

The paper designs a biohybrid materials circuit with binary decoder functionality using protease-based modules to detect small molecules and produce regulated protease outputs.

The paper provides the first structural characterization of the yeast peroxisomal docking complex Pex14p/Pex17p, revealing its subunit organization and potential role in import pore formation.