Author

Siyi Zhou

Rice UniversityORCID 0000-0002-7718-2864Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:metagenomics· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:software / tool· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Lauren B. StadleriD· 3 shared Todd J. TreangeniD· 2 shared Alice Liu· 1 shared Aylse Tran· 1 shared Bryce L. KilleiD· 1 shared Esther G. LouiD· 1 shared Fernanda Vaca· 1 shared Julia C. SchedleriD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersMicrobiology

Lauren B. StadlerORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Microfluidic Capture-Enrichment of individualized microbes from urban wastewater reveals a hidden reservoir of potential pre-emergent pathogens

Siyi Zhou, Seokju Seo, kathryn Rhatigan, Marga Lee, Alice Liu, Aylse Tran, Fernanda Vaca, Lois Armendariz, Todd J. Treangen, Natalia V. Kirienko, Lauren B. Stadler, Yousif E. Shamoo

The paper develops a microfluidic Capture-Enrichment pipeline to identify potential pre-emergent pathogens in urban wastewater, revealing clinically relevant threats and emerging phenotypes.

bioRxiv · Sep 23, 2026 · PreprintMicrobiology

Seqwin: Ultrafast identification of signature sequences in microbial genomes

Michael Wang, Bryce L. Kille, Michael Nute, Siyi Zhou, Lauren B. Stadler, Todd J. Treangen

Seqwin identifies microbial signature sequences by analyzing large genome collections, outperforming existing methods in efficiency and quality.

Bioinformatics · Jul 1, 2026Peer-reviewedBioinformatics

Comparative analysis of culture- and ddPCR-based wastewater surveillance for carbapenem-resistant bacteria

Siyi Zhou, Esther G. Lou, Julia C. Schedler, Katherine Bennett Ensor, Loren Hopkins, Lauren B. Stadler

This study compares culture-based and ddPCR methods for detecting carbapenem-resistant bacteria in wastewater, finding weak correlations between quantitative results due to method sensitivity and specificity differences.

Environmental Science Water Research & Technology · Aug 16, 2024Peer-reviewedMicrobiology