Natalia V. Kirienko

This study identifies a novel E3 ligase secreted by Pseudomonas aeruginosa that regulates virulence through ubiquitin modification.

The paper develops a microfluidic Capture-Enrichment pipeline to identify potential pre-emergent pathogens in urban wastewater, revealing clinically relevant threats and emerging phenotypes.

This study shows that P. aeruginosa liquid-based pathogenesis induces metabolic changes in C. elegans, involving lipid droplet depletion and HLH-30-dependent rewiring.

The paper identifies small molecules targeting AML by screening for compounds with predicted functions in apoptosis, glutathione metabolism, and autophagy, validating their efficacy in AML cells and patient-derived samples.

The paper identifies R5 pyocin production as a factor contributing to the dominance of high-risk Pseudomonas aeruginosa ST111 strains by exploiting O-antigen deficiency in competitors.

The paper identifies a gene network in C. elegans that supports mitochondrial health and links it to human diseases.

This study identifies five compounds that enhance Caenorhabditis elegans resistance to multiple pathogens by activating host defense pathways.

This study shows that a dietary vitamin B12 deficiency in C. elegans impairs mitochondrial function and stress resistance, which can be reversed by B12 supplementation.