Author

C. E. Lewis

University of Alabama

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Research Focus:host-pathogen & immune response· 1 Organism:plant (other)· 1 Assay:proteomics· 1

Frequent Co-Authors

A. A. Kuehl· 1 shared A. Egners· 1 shared A. Fragoulis· 1 shared A. Juncker-Jensen· 1 shared B. Gurel· 1 shared B. Pickering· 1 shared C. Bailey· 1 shared C. Embury-Hyatt· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. A. Kuehl

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Author profile →

4 papers

Recent·Most cited

Cas10 residues lining the target RNA binding channel regulate interference by distinguishing cognate target RNA from mismatched targets

Sarah A. Khweis, Mason Blackburn, Calvin Perdigao, Megan Pierce, C. E. Lewis, J.A. Dunkle

The paper identifies Cas10 residues that distinguish cognate from mismatched target RNAs, enhancing interference specificity in Type III CRISPR systems.

RNA Biology · Feb 18, 2026Peer-reviewedMolecular Biology

Targeting of a STING Agonist to Perivascular Macrophages in Prostate Tumors Delays Resistance to Androgen Deprivation Therapy

H. Al-janabi, K. Moyes, R. J. Allen, M. Fisher, M. Crespo, B. Gurel, P. Rescigno, J. De Bono, H. Nunns, C. Bailey, A. Juncker-Jensen, M. Muthana, W. A. Phillips, H. Pearson, M.-E. Taplin, , C. E. Lewis

This study shows targeting a STING agonist to perivascular macrophages in ADT-treated prostate tumors delays castration resistance prostate cancer onset.

bioRxiv · Apr 11, 2024Cancer Biology

Susceptibility of domestic swine to experimental infection with SARS-CoV-2

B. Pickering, G. Smith, M. Pinette, C. Embury-Hyatt, E. Moffat, P. Marszal, C. E. Lewis

This study shows that domestic pigs can be infected with SARS-CoV-2, with viral RNA and antibodies detected, highlighting the need for further livestock assessment in pandemic risk management.

bioRxiv · Sep 10, 2020 · PreprintMicrobiology

Non-canonical HIF-1 stabilization is essential for intestinal tumorigenesis

N. Rohwer, S. Jumpertz, M. Erdem, A. Egners, K. T. Warzecha, A. Fragoulis, A. A. Kuehl, R. Kramann, S. Neuss, I. Rudolph, T. Endermann, C. Zasada, I. Apostolova, M. Gerling, S. Kempa, , T. Cramer

This study shows that non-canonical HIF-1 stabilization is crucial for intestinal tumorigenesis, independent of hypoxia, by affecting both epithelial and microenvironmental oncogenic processes.

bioRxiv · Feb 28, 2018Cancer Biology