ImmunologybioRxivPreprint
BeWo-derived extracellular vesicles downregulate IL-6Rα expression via miRNAs on CD4+ T lymphocytes
Gábor Seregélyes, Bence Miklos Nagy, Árpád Ferenc Kovács…·Éva Pállinger
The paper shows BeWo-derived extracellular vesicles reduce IL-6Rα on CD4+ T cells via miRNAs, altering the IL-6 pathway and T cell function in vitro and correlating with pregnancy-associated IL-6R downregulation.
DOI 10.1101/2025.09.08.674438