Susana Muñoz Maniega

The paper shows that general cognitive function is supported by a widespread white matter network across multiple brain regions and connectivity measures.

This paper evaluates methods to estimate lifetime brain atrophy from a single MRI scan and identifies genetic correlates, finding that the residual method best captures brain shrinkage and has strong heritability.

The paper identifies brain regions most related to general cognitive function and links them to neurobiological properties using meta-analysis and multimodal cortical maps.

The paper develops epigenetic scores for GDF15 and NT-proBNP levels, showing associations with disease risks and brain health traits in two cohorts.

The paper identifies general and specific patterns of cortical gene expression related to cognitive functioning using principal component analysis and validates them across datasets.

This paper develops an epigenetic score to objectively measure alcohol consumption using blood-based DNA methylation and validates it across multiple cohorts, finding associations with brain health metrics.

This study identifies DNA methylation predictors of cognitive function using blood samples, showing they explain variance in cognitive ability and associate with biological markers.

The paper examines the association between birth weight and brain structure in older age, finding positive links with brain volumes but not with age-related structural changes.

This study identifies lipid biomarkers associated with brain structure but not cognitive ability in older adults using metabolomic data from the LBC1936 cohort.

This study examines age-related changes in PSMD across the adult lifespan using multi-cohort diffusion tensor imaging data, finding PSMD increases consistently while other metrics show different age patterns.

This study examines the genomic architecture of neuroanatomical diversity using SNP data and MRI, finding polygenic influences and environmental factors affecting brain asymmetry.

The paper quantifies perivascular spaces (PVS) in brain MRI and links them to retinal microvascular parameters in older adults, finding associations with arteriolar narrowing and reduced branching complexity.

The paper examines how aging affects brain network integrity and its association with cognitive function using MRI data from two cohorts.

This paper introduces DNAm GrimAge, an epigenetic clock that predicts mortality and is associated with multiple brain health measures in older adults.

The paper quantifies microstructural changes in normal-appearing white matter near white matter hyperintensities in older adults, showing spatial gradients of damage linked to WMH burden.

This study identifies neurology-related proteins in plasma associated with cognitive ability and brain volume in older adults, with partial mediation by brain volume.

The paper examines the association between brain peak width of skeletonised mean diffusivity (PSMD) and cognitive domains, finding it correlates with processing speed but not more strongly than other brain imaging measures or cognitive domains.

The paper matches 73- and 92-year-olds for childhood intelligence, social background, and brain size, finding significant structural brain differences linked to cognitive decline.

The paper evaluates 15 candidate SNPs associated with psychiatric disorders using 6,165 diffusion MRI scans, finding no significant associations after correction for multiple testing.