Author

Hidehiko Koizumi

National Institutes of HealthORCID 0000-0002-7747-3434Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:electronic health records· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:rat· 1

Frequent Co-Authors

Jeffrey C. SmithiD· 4 shared Yaroslav I. MolkoviD· 4 shared Ryan S. PhillipsiD· 2 shared Anke Borgmann· 1 shared Jonathan E. RubiniD· 1 shared Noriyuki Hama· 1 shared Ruli Zhang· 1 shared Tibin T. JohniD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 18 mutual co-author links

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4 shared papersNeuroscience

Jeffrey C. SmithORCID

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4 papers

Recent·Most cited

Functional Synaptic Interactions and Inhibitory Circuitry of the PreBötzinger Complex in the Rhythmic Slice

Yaroslav I. Molkov, Hidehiko Koizumi, Jeffrey C. Smith

The paper investigates synaptic interactions in the preBotzinger Complex using in vitro recordings, revealing a simplified inhibitory connectome compared to in situ conditions.

Journal of Neurophysiology · Jul 31, 2026Peer-reviewedNeuroscience

Inference technique for the synaptic conductances in rhythmically active networks and application to respiratory central pattern generation circuits

Yaroslav I. Molkov, Anke Borgmann, Hidehiko Koizumi, Noriyuki Hama, Ruli Zhang, Jeffrey C. Smith

The paper introduces a method to infer synaptic conductances from neuronal recordings and applies it to respiratory CPG circuits in rat brainstem.

eLife · Jul 2, 2025Peer-reviewedNeuroscience

Predictions and experimental tests of a new biophysical model of the mammalian respiratory oscillator

Ryan S. Phillips, Hidehiko Koizumi, Yaroslav I. Molkov, Jonathan E. Rubin, Jeffrey C. Smith

The paper tests and confirms three predictions of a biophysical model of the mammalian respiratory oscillator using optogenetic and pharmacological manipulations in neonatal mouse slices.

eLife · Jun 8, 2022Peer-reviewedNeuroscience

Biophysical mechanisms in the mammalian respiratory oscillator re-examined with a new data-driven computational model

Ryan S. Phillips, Tibin T. John, Hidehiko Koizumi, Yaroslav I. Molkov, Jeffrey C. Smith

The paper re-examines the roles of INaP and ICAN in respiratory rhythm generation using a new computational model, finding that ICAN affects amplitude while INaP drives rhythm.

eLife · Mar 25, 2019Peer-reviewedBioinformatics