Author

Samira Picht

Berlin-Brandenburger Centrum für Regenerative TherapienORCID 0000-0002-7761-5711Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Dimitrios L. WagneriD· 2 shared Hans‐Dieter VolkiD· 2 shared Jonas KathiD· 2 shared Michael Schmueck‐HenneresseiD· 2 shared Abdolreza Nazari· 1 shared Anamika Giri· 1 shared Andrea Sánchez PeñaiD· 1 shared Andriko PalmowskiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Dimitrios L. WagnerORCID

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2 papers

Recent·Most cited

ImmunologyMolecular Therapy AdvancesPeer-reviewedApr 9, 2026

Clinical development of gene edited tacrolimus-resistant Treg (FKBP12KO-Treg) to enable simultaneous immunosuppression and support of immune regulation

Ghazaleh Zarrinrad, Lisa-Marie Burkhardt, C. Beltran-Mestres…·Leila Amini

This paper develops gene-edited tacrolimus-resistant Treg cells (FKBP12KO-Treg) for clinical use in transplant recipients, showing they maintain immunoregulatory function while resisting tacrolimus.

2 citationstop 5%

humanflow cytometry

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BioengineeringMolecular Therapy — Nucleic AcidsPeer-reviewedJan 5, 2026

Revisiting the need for mRNA nucleoside modification in CAR T cell engineering

Nourhan Kahwaji, Niklas Kotzian, Jasmin Melissa Prinz…·Norman Michael Drzeniek

This study shows that unmodified mRNA can be used for CAR-T cell engineering without compromising function, eliminating the need for costly nucleoside modifications.

7 citationstop 1%

humanbulk RNA-seq

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