Author

Masahiro Takayama

Shionogi (Japan)ORCID 0000-0002-7764-1610Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Takeshi Ishihara· 2 shared Takeshi OtaiD· 2 shared Haruhiko KamadaiD· 1 shared Haruyo Konishi· 1 shared Keita FukaoiD· 1 shared Kentaro Furukawa· 1 shared Mai YoshikawaiD· 1 shared Masaaki SatoiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

Takeshi Ishihara

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Discovery of anti-SARS-CoV-2 S2 protein antibody CV804 with broad-spectrum reactivity with various beta coronaviruses and analysis of its pharmacological properties in vitro and in vivo

Yoji Tsugawa, Kentaro Furukawa, Tomoko Ise, Masahiro Takayama, Takeshi Ota, Takayuki Kuroda, Shinya Shano, Takashi Hashimoto, Haruyo Konishi, Takeshi Ishihara, Masaaki Sato, Haruhiko Kamada, Keita Fukao, Takao Shishido, Mai Yoshikawa, , Satoshi Nagata

This study identifies an antibody, CV804, that targets the conserved S2 domain of coronaviruses and shows broad cross-reactivity and ADCC activity against SARS-CoV-2 and related viruses.

PLoS ONE · Dec 2, 2024Peer-reviewedMicrobiology

Enabling Epitope Analysis of Glycoproteins via HDX-MS Using Antigens with Uni-formed N-linked Glycans

Takeshi Ota, Masahiro Takayama, Takeshi Ishihara, Masaaki Sato, Sawaka Ono, Ryota Futamata, Masaya Fujitani, Masatomo Rokushima

This study shows that using antigens with uniform N-linked glycans improves epitope analysis of glycoproteins via HDX-MS, identifying epitopes including previously reported glycan sites for a monoclonal antibody.

bioRxiv · Sep 24, 2024 · PreprintBiochemistry