Masaaki Sato

Dual roles of idling moments in past and future memories

The paper shows that in mice, preconfigured engram cell ensembles during sleep correlate with learning, and postlearning synaptic changes prepare for new memories.

Enabling Epitope Analysis of Glycoproteins via HDX-MS Using Antigens with Uni-formed N-linked Glycans

This study shows that using antigens with uniform N-linked glycans improves epitope analysis of glycoproteins via HDX-MS, identifying epitopes including previously reported glycan sites for a monoclonal antibody.

Dynamic population coding of social novelty in the insular cortex

The paper investigates how neurons in the agranular insular cortex distinguish between familiar and novel social conspecifics using calcium imaging in mice during social recognition memory and discrimination tasks.

VR-based real-time imaging reveals abnormal cortical dynamics during behavioral transitions in a mouse model of autism

The paper uses VR-based real-time imaging to study cortical functional connectivity dynamics during behavioral transitions in a mouse model of autism, finding altered FC patterns in motor areas associated with motor clumsiness.

HOTARU: Automatic sorting system for large scale calcium imaging data

The paper introduces an improved CNMF-based algorithm for calcium imaging data analysis, enhancing cell detection accuracy and signal quality.

Sublayer- and cell-type-specific neurodegenerative transcriptional trajectories in hippocampal sclerosis

The paper identifies sublayer- and cell-type-specific transcriptional changes in hippocampal sclerosis using single-nucleus and bulk RNA sequencing, revealing distinct neurodegenerative trajectories in superficial CA1 neurons.

Encoding of social exploration by neural ensembles in the insular cortex

The paper identifies two subsets of insular cortex neurons in mice that encode social exploration behavior differently during interactions with social targets.

Wide and Deep Imaging of Neuronal Activities by a Wearable NeuroImager Reveals Premotor Activity in the Whole Motor Cortex

The paper introduces a wearable neuroimager for whole-brain imaging in mice, revealing premotor activity across the motor cortex.

Dynamic embedding of salience coding in hippocampal spatial maps

The paper investigates how hippocampal CA1 neurons dynamically represent and stabilize spatial maps in mice learning a virtual-reality navigation task, showing that salient experiences like rewards reshape these maps through selective consolidation.

Automatic sorting system for large calcium imaging data

The paper improves cell activity estimation in calcium imaging data using non-negative matrix decomposition with shrinkage estimation and enhanced initialization methods.