Author

James R. Bradford

Almac (United Kingdom)ORCID 0000-0002-7771-914XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

A.R. Phillips· 1 shared Alice T. Browne· 1 shared Alyson SpeediD· 1 shared Carla P. MartinsiD· 1 shared Catherine Joan Davidson· 1 shared Chris McCann· 1 shared Connor N. BrowniD· 1 shared D LambertiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A.R. Phillips

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2 papers

Recent·Most cited

Mutant KRAS dosage contributes to heterogeneity in lung cancer therapeutic response

Alice T. Browne, Chris McCann, William J. McDaid, Nikita Lewis, Sandhya Sridhar, Gary Joseph Doherty, Deborah Y. Moss, Matilda Downs, Stephen Marry, A.R. Phillips, Connor N. Brown, Alyson Speed, Gemma E. Logan, Gera L. Jellema, James R. Bradford, , Emma M. Kerr

This study shows that mutant KRAS dosage affects therapeutic response in lung cancer, with higher dosages linked to resistance to platinum therapy and sensitivity to pS6K inhibition.

bioRxiv · May 9, 2026 · PreprintCancer Biology

Comprehensive functional profiling of long non-coding RNAs through a novel pan-cancer integration approach and modular analysis of their protein-coding gene association networks

Kevin Walters, Radmir Sarsenov, Wen Siong Too, Roseanna K. Hare, Ian Charles Paterson, D Lambert, Stephen Brown, James R. Bradford

The paper integrates gene expression across 32 cancer types to identify 16 lncRNA modules, revealing four functional themes and potential roles in tumour progression.

BMC Genomics · Jun 3, 2019Peer-reviewedBioinformatics