Author

Frank Loesche

Howard Hughes Medical InstituteORCID 0000-0002-7780-6438Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:database / resource· 2 Assay:imaging· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

Alanna LohffiD· 2 shared Alexander ThomsoniD· 2 shared Alexandra M. C. FragniereiD· 2 shared Aljoscha NerniD· 2 shared Arthur ZhaoiD· 2 shared Ashley L ScottiD· 2 shared Brandon S CaninoiD· 2 shared C. Shan XuiD· 2 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Alanna LohffORCID

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3 papers

Recent·Most cited

Sexual dimorphism in the complete connectome of the Drosophila male central nervous system

Stuart Berg, Isabella R. Beckett, Marta Costa, Schlegel Philipp, Michał Januszewski, Elizabeth C. Marin, Aljoscha Nern, Stephan Preibisch, Wei Qiu, Shin-ya Takemura, Alexandra M. C. Fragniere, Andrew S Champion, Diane-Yayra Adjavon, Michael Cook, Marina Gkantia, , Sandro Romani

The paper presents the complete connectome of the Drosophila male central nervous system and compares it to the female connectome, identifying sex-specific and dimorphic neuronal types.

Cell · Sep 1, 2026Peer-reviewedNeuroscience

Connectome-driven neural inventory of a complete visual system

Aljoscha Nern, Frank Loesche, Shin-ya Takemura, Laura E. Burnett, Marisa Dreher, Eyal Gruntman, Judith Hoeller, Gary B. Huang, Michał Januszewski, Nathan C Klapoetke, Sanna Koskela, Kit D. Longden, Zhiyuan Lu, Stephan Preibisch, Wei Qiu, , Michael B. Reiser

A FIB-SEM connectome of the male Drosophila right optic lobe sorts ∼53,000 neurons into 727 types, with neurotransmitter predictions and 577 matched split-GAL4 lines.

Nature · Mar 26, 2025Peer-reviewedNeuroscience✦ In-depth digest

A high-speed, modular display system for diverse neuroscience applications

Matthew D. Isaacson, Lisa Ferguson, Frank Loesche, Ishani Ganguly, Jim Hao Chen, Andy Chiu, Jinyang Liu, William B. Dickson, Michael B. Reiser

This paper introduces a modular LED display system for neuroscience experiments, enabling precise visual stimulation and behavioral analysis in Drosophila.

bioRxiv · Aug 2, 2022 · PreprintNeuroscience