Aljoscha Nern

The organization of visual pathways in the Drosophila brain

The paper uses a Drosophila connectome to analyze visual pathway organization, revealing multi-layered, functionally interpretable pathways that transform visual input into perceptual representations.

Sexual dimorphism in the complete connectome of the Drosophila male central nervous system

The paper presents the complete connectome of the Drosophila male central nervous system and compares it to the female connectome, identifying sex-specific and dimorphic neuronal types.

Parallel neuronal ensembles control behavior across sensorimotor levels in Drosophila

The paper compares neuronal circuits for landing and takeoff in Drosophila, revealing parallel ensembles that enable flexible behavioral control.

Synaptic Targets of Circadian Clock Neurons Influence Core Clock Parameters

This study identifies SLP316 neurons as synaptic targets of circadian clock neurons in Drosophila, showing that modulating their activity alters circadian period and behavior.

Cell type-specific driver lines targeting the Drosophila central complex and their use to investigate neuropeptide expression and sleep regulation

The paper generates and characterizes split-GAL4 driver lines for specific Drosophila central complex cell types, surveys neuropeptide and receptor expression, and identifies cell types involved in sleep regulation.

Connectome-driven neural inventory of a complete visual system

A FIB-SEM connectome of the male Drosophila right optic lobe sorts ∼53,000 neurons into 727 types, with neurotransmitter predictions and 577 matched split-GAL4 lines.

A split-GAL4 driver line resource for Drosophila neuron types

The paper describes a collection of split-GAL4 driver lines for targeting specific neuron types in Drosophila, enabling functional and molecular studies.

Connectomic reconstruction predicts the functional organization of visual inputs to the navigation center of the Drosophila brain

The paper reconstructs the connectome of the Drosophila anterior visual pathway to understand how visual inputs are processed for navigation.

Social state gates vision using three circuit mechanisms in Drosophila

The paper identifies three circuit mechanisms in Drosophila that adjust visual attention during aggressive states by amplifying responses to fly-sized visual objects.

Synergy of color and motion vision for detecting approaching objects in Drosophila

This study shows that color enhances motion vision in Drosophila by improving detection of approaching UV discs through synergistic pathways between UV-sensitive photoreceptors and motion-sensitive neurons.

A comprehensive neuroanatomical survey of the Drosophila Lobula Plate Tangential Neurons with predictions for their optic flow sensitivity

The paper reconstructs and identifies 58 Lobula Plate Tangential Neurons in Drosophila using EM and predicts their optic flow sensitivity through computational anatomy.

Identifying determinants of synaptic specificity by integrating connectomes and transcriptomes

The paper identifies synaptic specificity determinants by integrating connectomes and transcriptomes in Drosophila.

A competitive disinhibitory network for robust optic flow processing in Drosophila

The paper identifies a competitive disinhibitory network in Drosophila that enhances rotational optic flow processing for navigation.

Small-field visual projection neurons detect translational optic flow and support walking control

The paper identifies a cell type in Drosophila that detects translational optic flow and is essential for forward walking.

BigNeuron: A resource to benchmark and predict best-performing algorithms for automated reconstruction of neuronal morphology

BigNeuron benchmarks automatic neuron reconstruction algorithms using gold standard annotations and image quality metrics, showing that consensus methods outperform individual algorithms.

A searchable image resource of Drosophila GAL4-driver expression patterns with single neuron resolution

The paper provides a searchable image resource of Drosophila GAL4-driver expression patterns at single neuron resolution to improve cell type identification and split-GAL4 combination prediction.

Eye structure shapes neuron function in Drosophila motion vision

The paper shows that the preferred directions of Drosophila DS neurons are shaped by the compound eye's structure, linking peripheral anatomy to neural function and behavior.

Axon arrival times and physical occupancy establish visual projection neuron integration on developing dendrites in the Drosophila optic glomeruli.

The paper shows that sequential axon arrival and physical occupancy determine the integration of visual projection neurons onto the dendrites of the giant fiber in Drosophila.

Neural Network Organization for Courtship Song Feature Detection in Drosophila

The paper maps the auditory pathway in Drosophila, identifies new cell types, and reveals a network of neurons with continuous song mode preferences and non-hierarchical connectivity.

Neuronal circuits integrating visual motion information in Drosophila

This study identifies synaptic connections of T4/T5 neurons in Drosophila, revealing new cell types and connectivity patterns that explain motion signal integration in the visual system.

Synaptic targets of photoreceptors specialized to detect color and skylight polarization in Drosophila

The paper maps synaptic targets of color and polarization-sensitive photoreceptors in Drosophila, revealing modality-specific wiring and spatial segregation in neural circuits.

An unbiased template of the Drosophila brain and ventral nerve cord

This paper creates high-resolution brain and ventral nerve cord templates for Drosophila using advanced imaging and registration techniques, showing improved accuracy and efficiency compared to existing templates.

Connectivity establishes spatial readout of visual looming in a glomerulus lacking retinotopy

The paper investigates how spatial information is processed in a Drosophila glomerulus lacking retinotopy, finding that connectivity preserves spatial readout of visual looming.

The connectome of the adult Drosophila mushroom body: implications for function

The paper maps the synaptic connectivity of the Drosophila mushroom body and identifies new circuit components and structures in sensory input processing and output modulation.

A genetic, genomic, and computational resource for exploring neural circuit function

The paper characterizes gene expression in 67 Drosophila visual system cell types using TAPIN-seq and genetic drivers, building a transcriptome resource to study neural circuit function.

Stem cell intrinsic, Seven-up-triggered temporal factor gradients diversify intermediate neural progenitors

The paper identifies temporal RNA-binding protein gradients in Drosophila neuroblasts that regulate intermediate neural progenitor fate.