Tao Yang

This study maps the functional effects of thousands of KCNE1 variants using high-throughput methods, identifying loss-of-function and loss-of-surface expression variants and showing concordance with electrophysiological and computational data.

This study shows that Dscam overexpression in Down syndrome mouse models causes excessive GABAergic inhibition of neocortical pyramidal neurons.

The paper uses genetic labeling and high-resolution microscopy to reveal fine-grained subtypes of cortical interneurons in mice, showing distinct connectivity patterns.