Mike L. Smith

This paper provides an overview of single-cell RNA sequencing analysis using Bioconductor, highlighting its tools and methods for handling high-dimensional data.

The paper introduces beachmat, a C++ API for efficient access to single-cell genomics data in various R matrix formats, demonstrating its performance and integration capabilities.

Telomerecat estimates telomere length from whole-genome sequencing data without requiring prior knowledge of ploidy, showing good performance and detecting expected patterns in various data types.