RNA-binding proteins provide specificity to the PAN2-PAN3 mRNA deadenylation complex
Terence T. L. Tang, Francesco Zangari, Conny Wing-Heng Yu, James A. W. Stowell, Alžběta Roeselová, Stefan M.V. Freund, Anne‐Claude Gingras, Lori A. Passmore
This study shows that the PAN2-PAN3 deadenylation complex can be recruited to specific mRNAs via RNA adaptors, adding to the specificity of mRNA degradation.
bioRxiv · Sep 27, 2025 · PreprintMolecular Biology