Anh Hai Vu

The paper demonstrates multiplexing single-cell RNA-seq and metabolomics on the same plant cell to directly correlate gene expression and metabolite levels.

This study uses single cell mass spectrometry to investigate the intercellular compartmentalization of camptothecin biosynthesis in the tree Camptotheca acuminata and identifies cell-specific metabolite distributions.

The paper demonstrates the use of single cell mass spectrometry to track isotopic labeling in plant protoplasts, showing the synthesis and transport of alkaloids over 24 hours.

The paper develops a method for single cell mass spectrometry to quantify natural products in plant cells, revealing biosynthetic dynamics not captured by scRNA-seq.