Thu‐Thuy T. Dang

This paper engineers yeast to produce strictosidinic acid, a key anticancer drug intermediate, achieving 548 mg/L through metabolic pathway optimization and strain engineering.

The paper uses single-cell multi-omics to identify rare cell types involved in camptothecin biosynthesis in Camptotheca acuminata.

This study uses single cell mass spectrometry to investigate the intercellular compartmentalization of camptothecin biosynthesis in the tree Camptotheca acuminata and identifies cell-specific metabolite distributions.