Author

Mark A. Varney

Neurolixis (United States)ORCID 0000-0002-7818-5266Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Adrian Newman‐TancrediiD· 2 shared André Vidinha‐MiraiD· 2 shared Andreia Teixeira‐CastroiD· 2 shared Bruna Ferreira-LombaiD· 2 shared Daniela Cunha‐GarciaiD· 2 shared Daniela Monteiro‐FernandesiD· 2 shared Mark S. KleveniD· 2 shared Patrı́cia MacieliD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Adrian Newman‐TancrediORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 4, 2025

The 5-HT1A receptor agonist NLX-112 rescues motor swimming deficits in Spinocerebellar Ataxia type 3 mice

Daniela Cunha‐Garcia, Bruna Ferreira-Lomba, Sara R. Guerreiro…·Adrian Newman‐Tancredi

This study tests the 5-HT1A agonist NLX-112 in SCA3 mice, finding it improves motor performance in a swimming test.

DOI 10.1101/2025.09.04.674027

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintAug 21, 2025

Efficacy of chronic 5-HT1A receptor agonism by NLX-112 in a mouse model of Spinocerebellar Ataxia type 3

Bruna Ferreira-Lomba, Sara R. Guerreiro, Sara Duarte‐Silva…·Patrı́cia Maciel

This study evaluates NLX-112, a 5-HT1A receptor agonist, in a mouse model of SCA3, showing improved motor function and neuroprotection when administered pre-symptomatically.

1 citation

mouseexperimental assay

𝕏 PostBluesky