Pohao Ye

Sequential evolution of antidote and toxin links genetic incompatibility with immune responses

The paper discovers a novel toxin-antidote gene pair in C. nigoni, showing the antidote evolved before the toxin and supports a microbial origin for the toxin.

A Newborn F-box Gene Blocks Gene Flow by Selectively Degrading Phosphoglucomutase in Species Hybrids

This paper shows a new F-box gene in C. nigoni causes hybrid incompatibility by degrading a phosphoglucomutase from C. briggsae, leading to embryonic death in hybrids.

EmbSAM: Cell boundary localization and Segment Anything Model for fast images of developing embryos

EmbSAM provides a framework for 3D cell membrane segmentation in C. elegans embryos using deep learning and the Segment Anything Model, enabling analysis of cell shape dynamics during development.

Genomic architecture of 5S rDNA cluster and its variations within and between species

The paper characterizes the genomic structure and variation of the 5S rDNA cluster in C. elegans and C. briggsae strains, revealing differences in stability and transcriptional compatibility.