Author

Alejandro Álvarez-Prats

National Institutes of HealthORCID 0000-0002-7846-8346Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Alexandria L ShawiD· 1 shared Calvin K. YipiD· 1 shared John E. BurkeiD· 1 shared Joshua G. PembertoniD· 1 shared Mackenzie K. ScottiD· 1 shared Matthew AH ParsoniD· 1 shared Meredith L. JenkinsiD· 1 shared Noah J HarrisiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Alexandria L ShawORCID

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1 paper

Recent·Most cited

Molecular basis for plasma membrane recruitment of PI4KA by EFR3

Sushant Suresh, Alexandria L Shaw, Joshua G. Pemberton, Mackenzie K. Scott, Noah J Harris, Matthew AH Parson, Meredith L. Jenkins, Pooja Rohilla, Alejandro Álvarez-Prats, Tamás Balla, Calvin K. Yip, John E. Burke

The paper reports a cryo-EM structure of EFR3A bound to the PI4KA complex, revealing the molecular mechanism of PI4KA membrane recruitment and its regulation in human disease.

Science Advances · Dec 20, 2024Peer-reviewedBiochemistry