Urmas Roostalu

The paper evaluates biomarkers in a mouse model of diabetic kidney disease and HFpEF, finding that suPAR levels correlate with disease severity.

This paper develops a 3D imaging and deep learning method to quantify cardiac fibrosis in mice and shows semaglutide reduces hypertrophy and perivascular fibrosis but not replacement fibrosis.

The paper maps molecular gradients and spatial organization in the subthalamic and para-subthalamic regions across species, identifying conserved and species-specific patterns.

The paper develops TRIC-DISCO, a pipeline for whole-brain 3D RNA imaging in adult mice, enabling single-cell resolution of transcriptional signatures and markers without strict RNase-free conditions.