Author

Casper Graversen Salinas

Gubra (Denmark)ORCID 0000-0003-3485-8331Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:dimensionality reduction· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Research Focus:imputation· 1

Frequent Co-Authors

Jacob Hecksher‐SørenseniD· 2 shared Jacob Lercke SkytteiD· 2 shared Urmas RoostaluiD· 2 shared Abigail WaltoniD· 1 shared Allan Jensen· 1 shared Ayako Miyakawa· 1 shared Camilla Stampe JenseniD· 1 shared Dagmara KaczyńskaiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Jacob Hecksher‐SørensenORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Deep Learning-Enhanced 3D Imaging Unveils Semaglutide Impact on Cardiac Fibrosis

Sheyla Barrado Ballestero, Sarah Torp Yttergren, Max Hahn, Marie Biviano Rosenkilde, Ditte Marie Jensen, Michael Søberg Christensen, Louise Thisted, Heidi Lindgreen Holmberg, Geoffrey Teixeira, Tor Biering‐Sørensen, Casper Graversen Salinas, Urmas Roostalu

This paper develops a 3D imaging and deep learning method to quantify cardiac fibrosis in mice and shows semaglutide reduces hypertrophy and perivascular fibrosis but not replacement fibrosis.

British Journal of Pharmacology · Oct 21, 2025Peer-reviewedPathology

Transferrin receptor-binding blood-brain barrier shuttle enhances brain delivery and efficacy of a therapeutic anti-Abeta antibody

Marta Ramos Vega, Henrik H. Hansen, Camilla Stampe Jensen, Evdoxia Alexiou, Martin Rønn Madsen, Franziska Wichern, Jacob Lercke Skytte, Casper Graversen Salinas, Florence Sotty, Allan Jensen, Sandra B. Vergo, Jacob Hecksher‐Sørensen

This study shows that fusing an anti-Aβ antibody to a TfR1-binding Fab fragment enhances brain delivery and plaque clearance while reducing adverse effects in APP/PS1 mice.

bioRxiv · Feb 14, 2025 · PreprintNeuroscience

Whole-Brain Three-Dimensional Imaging of RNAs at Single-Cell Resolution

Shigeaki Kanatani, Judith C. Kreutzmann, Yue Li, Zoe Elizabeth West, Lea Lydolph Larsen, Danai Vougesi Nikou, Ilse Eidhof, Abigail Walton, Songbai Zhang, Leslie A. Kirby, Jacob Lercke Skytte, Casper Graversen Salinas, Kimiharu Takamatsu, Xiaofei Li, Daisuke H. Tanaka, , Per Uhlén

The paper develops TRIC-DISCO, a pipeline for whole-brain 3D RNA imaging in adult mice, enabling single-cell resolution of transcriptional signatures and markers without strict RNase-free conditions.

Science · Nov 21, 2024Peer-reviewedNeuroscience