Efficient differentiation and polarization of primary cultured neurons on poly(lactic acid) scaffolds with microgrooved structures
Asako Otomo, Mahoko Takahashi Ueda, Toshinori Fujie, Arihiro Hasebe, Yoshitaka Suematsu, Yosuke Okamura, Shinji Takeoka, Shinji Hadano, So Nakagawa
This study shows that microgrooved PLA nanosheets enhance neuronal differentiation and gene expression related to synaptic structures compared to flat nanosheets.
Scientific Reports · Apr 21, 2020Peer-reviewedMolecular Biology