Cell BiologybioRxivPreprint
Upregulation of the lncRNA XACT sustains pluripotency, blocks lineage specification, and drives germ cell tumor-like transcriptional programs in human pluripotent stem cells
DOI 10.1101/2025.10.02.679492
Author
Tokai UniversityORCID 0009-0006-6098-4242Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Nami Motosugi, Keita Hasegawa, Natsumi Kurosaki…·Atsushi Fukuda
The paper develops a method to efficiently reactivate XIST in female hPSCs by inhibiting TP53 and DNA methylation during Cas9-mediated genome editing.
Akira Oka, Atsushi Takagi, Etsuko Komiyama…·Shigaku Ikeda
The paper identifies a susceptibility variant in CCHCR1 associated with alopecia areata and shows its effect in mice with patched hair loss.