Pharmacology & ToxicologyCell CalciumPeer-reviewed
TRPV4 Promotes Histamine Receptor Signaling in Lymphatic Endothelial Cells
Jeffri S. Retamal, Scott Peng, Thanh-Nhan Nguyen…·Daniel P. Poole
This study shows TRPV4 mediates histamine receptor signaling in lymphatic endothelial cells, enhancing Ca2+ signaling and NFATc1 translocation while cytokine release occurs through distinct mechanisms.
DOI 10.1016/j.ceca.2026.103184