NeurosciencebioRxivPreprint
Senescent Schwann cells induced by aging and chronic denervation impair axonal regeneration after peripheral nerve injury
Andrés Fuentes-Flores, Cristian Gerónimo‐Olvera, David Ñecuñir…·Felipe A. Court
This study shows that senescent Schwann cells, induced by aging and chronic denervation, impair axonal regeneration by reducing c-Jun expression and secreting inhibitory factors, and that eliminating these cells improves regeneration.
1 citation