Author

Alexander Kowar

German Cancer Research CenterORCID 0000-0002-7868-3935Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Fabricio Loayza‐PuchiD· 2 shared Rossella Del Pizzo· 2 shared Ali Hyder Baig· 1 shared Andres M. EliaiD· 1 shared Angelika Beate RiemeriD· 1 shared Ariel Galindo‐AlbarrániD· 1 shared Beiping MiaoiD· 1 shared Catarina PechinchaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Fabricio Loayza‐PuchORCID

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2 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedAug 27, 2025

Upstream open reading frame translation enhances immunogenic peptide presentation in mitotically arrested cancer cells

Alexander Kowar, Jonas Philipp Becker, Rossella Del Pizzo…·Fabricio Loayza‐Puch

The paper shows that mitotic arrest in cancer cells enhances uORF/uoORF translation, leading to increased immunopeptide presentation and T-cell mediated killing.

10 citations

humanproteomics

Cancer BiologyNature CommunicationsPeer-reviewedMay 19, 2025

Dual Ribosome Profiling reveals metabolic limitations of cancer and stromal cells in thetumor microenvironment

Daniela Avilés Huerta, Rossella Del Pizzo, Alexander Kowar…·Fabricio Loayza‐Puch

This study uses Dual Ribosome Profiling to reveal cell type-specific metabolic limitations in the tumor microenvironment, showing how amino acid availability affects immunotherapy outcomes.

3 citations

mouseproteomics