Eric F. Schmidt

The paper identifies divergent mitochondrial and metabolic profiles between ALS-vulnerable and resilient neurons, revealing how these differences contribute to selective vulnerability in ALS.

The paper identifies a class of spontaneously regenerative corticospinal neurons in mice that project ipsilaterally and share molecular features with embryonic-like regenerating neurons.

The paper identifies molecular differences between two populations of motor cortical layer 5b neurons in an ALS model, showing Oxphos pathway regulation and reactive oxygen species handling as factors in selective degeneration.

This study identifies a functional gene module associated with selective neuronal vulnerability in Alzheimer’s disease using integrated molecular and genetic data from mice and humans.

This study shows that knocking out 5-HT4R in mature hippocampal excitatory neurons leads to anxiety-like behaviors and neural dysfunction.