A multi-track landscape of haematopoiesis informed by cellular barcoding and agent-based modelling
Dawn S. Y. Lin, Stephen Zhang, Jaring Schreuder, Jessica Tran, Tobias Sargeant, Don Metcalf, Ashley P. Ng, Tom S. Weber, Shalin H. Naik
This study uses cellular barcoding and agent-based modeling to reveal clonal fate patterns in hematopoiesis, showing that stem and progenitor cells are often less multipotent than previously thought.
bioRxiv · Mar 28, 2024 · PreprintImmunology