Tuan Vo

SpaMTP: Integrative Statistical Analysis and Visualisation of Spatial Metabolomics and Transcriptomics data.

SpaMTP integrates spatial metabolomics and transcriptomics data through a comprehensive analysis pipeline and visualization tools.

Unraveling lncRNA Diversity at a Single Cell Resolution and in a Spatial Context across Different Cancer Types

The paper identifies 354,937 novel lncRNAs across 13 cancer types using single-cell and spatial transcriptomics, revealing their cell-type specificity, spatial distribution, and potential functional roles.

Spatial pharmaco-multiomics reveals drug distribution, metabolic niches, and spatially constrained resistance in medulloblastoma

This study develops a spatial pharmaco-multiomics framework to map drug distribution, metabolic niches, and resistance mechanisms in medulloblastoma using integrated spatial and transcriptomic data.

Integrating 12 Spatial and Single Cell Technologies to Characterise Tumour Neighbourhoods and Cellular Interactions in three Skin Cancer Types

The paper integrates 12 spatial and single-cell technologies to analyze cellular interactions and signatures in three skin cancers, identifying key therapeutic targets and genetic associations.

A systemic clock brake: Period1 stabilizes the circadian network under environmental stress

This study identifies Per1 as a systemic regulator of circadian stability, showing that its loss accelerates clock realignment and protects against jetlag-related disruptions.

Spatial Transcriptomic Sequencing of a DIPG-infiltrated Brainstem reveals Key Invasion Markers and Novel Ligand-Receptor Pairs contributing to Tumour to TME Crosstalk

This study uses spatial transcriptomics to analyze a DIPG-infiltrated brainstem, identifying invasion markers and ligand-receptor pairs involved in tumour-TME crosstalk.

A robust Platform for Integrative Spatial Multi-omics Analysis to Map Immune Responses to SARS-CoV-2 infection in Lung Tissues

This paper develops a spatial multi-omics platform to analyze immune responses in SARS-CoV-2-infected lung tissues, revealing macrophage infiltration and spatial heterogeneity in cytokine and interferon signaling.

Spatial transcriptomic analysis of Sonic Hedgehog Medulloblastoma identifies that the loss of heterogeneity and promotion of differentiation underlies the response to CDK4/6 inhibition

The paper uses spatial transcriptomics to analyze how CDK4/6 inhibition affects tumor response in SHH medulloblastoma by mapping cellular states and spatial organization.