Author

Cheng‐Ting Chien

Institute of Molecular Biology, Academia SinicaORCID 0000-0002-7906-7173Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Pei‐Yi CheniD· 2 shared Yi-Wei TsaiiD· 2 shared Ying-Ju ChengiD· 2 shared Angela GiangrandeiD· 1 shared Chun-Yen Yeh· 1 shared Chun‐Hong CheniD· 1 shared Hsin-Ho SungiD· 1 shared Jian‐Chiuan LiiD· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 31 mutual co-author links

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2 shared papersDevelopmental Biology

Pei‐Yi ChenORCID

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2 papers

Recent·Most cited

Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and responses to hypoxia

Yi-Wei Tsai, Hsin-Ho Sung, Jian‐Chiuan Li, Chun-Yen Yeh, Pei‐Yi Chen, Ying-Ju Cheng, Chun‐Hong Chen, Yu-Chen Tsai, Cheng‐Ting Chien

This study identifies glia-derived exosomal miR-274 as a regulator of synaptic bouton and tracheal branch growth, and shows it modulates larval hypoxia responses by targeting Sprouty.

Proceedings of the National Academy of Sciences · Oct 30, 2019Peer-reviewedDevelopmental Biology

Glial response to hypoxia in trachealess mutants induces synapse remodeling.

Pei‐Yi Chen, Yi-Wei Tsai, Ying-Ju Cheng, Angela Giangrande, Cheng‐Ting Chien

The paper shows that hypoxia in Drosophila trh mutants causes glial-induced synaptic remodeling through HIF-1/Sima and Wg signaling, maintaining synaptic transmission for larval locomotion.

PLoS Genetics · Aug 5, 2019Peer-reviewedGenetics