Pei‐Yi Chen

The paper introduces GenomicLLM, a large language model trained on genomic and natural language data, capable of performing various analysis tasks with comparable performance to existing tools.

This study identifies glia-derived exosomal miR-274 as a regulator of synaptic bouton and tracheal branch growth, and shows it modulates larval hypoxia responses by targeting Sprouty.

The paper shows that hypoxia in Drosophila trh mutants causes glial-induced synaptic remodeling through HIF-1/Sima and Wg signaling, maintaining synaptic transmission for larval locomotion.