Chun‐Hong Chen

This paper demonstrates that adaptive sampling-based sequencing enables efficient genome reconstruction of intracellular symbionts from host-dominated samples, achieving high completeness and revealing structural divergence from reference genomes.

This study sequenced 1,206 Aedes aegypti genomes to trace the origin and global spread of the species, revealing its evolution from a forest-dwelling to an urban, human-biting form and its impact on dengue risk.

The paper identifies novel persistent viruses in Aedes aegypti mosquitoes using small RNA sequencing and confirms their replication and transmissibility in cell lines.

This study uses a value-based feeding decision assay to assess cognitive decline in Drosophila, showing its correlation with aging and neurodegenerative disorders and demonstrating potential neuroprotective interventions.

This study identifies glia-derived exosomal miR-274 as a regulator of synaptic bouton and tracheal branch growth, and shows it modulates larval hypoxia responses by targeting Sprouty.

This study generates Ae. aegypti mosquitoes engineered with synthetic miRNAs to reduce ZIKV infection, dissemination, and transmission.