Author

Felice Ho‐Ching Tsang

John Radcliffe HospitalORCID 0000-0002-7915-6782Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Benjamin DaviesiD· 2 shared Douglas R. HiggsiD· 2 shared Mira T. KassoufiD· 2 shared Rosa J. StolperiD· 2 shared Caroline L. HarroldiD· 1 shared Damien J. DownesiD· 1 shared Emily GeorgiadesiD· 1 shared Helena S. FrancisiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersMolecular Biology

Benjamin DaviesORCID

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2 papers

Recent·Most cited

The characteristics of CTCF binding sequences contribute to enhancer blocking activity

Felice Ho‐Ching Tsang, Rosa J. Stolper, Muhammad Hanifi, Lucy Cornell, Helena S. Francis, Benjamin Davies, Douglas R. Higgs, Mira T. Kassouf

This study identifies CTCF binding sequences that effectively block enhancer-promoter activity, showing that their function is not correlated with CTCF/cohesin levels, conservation, or sequence similarity to consensus motifs.

Nucleic Acids Research · Jul 22, 2024Peer-reviewedMolecular Biology

Loop extrusion by cohesin plays a key role in enhancer-activated gene expression during differentiation

Rosa J. Stolper, Felice Ho‐Ching Tsang, Emily Georgiades, Lars L.P. Hansen, Damien J. Downes, Caroline L. Harrold, Jim R. Hughes, Robert A. Beagrie, Benjamin Davies, Mira T. Kassouf, Douglas R. Higgs

The paper investigates the role of cohesin-mediated loop extrusion in enhancer-promoter proximity and gene expression during mouse erythropoiesis, finding that it is important but not exclusive for gene activation.

bioRxiv · Sep 7, 2023 · PreprintMolecular Biology