Author

Lucy Cornell

John Radcliffe HospitalORCID 0000-0002-8561-5607Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Assay:DNA methylation· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Douglas R. HiggsiD· 2 shared Helena S. FrancisiD· 2 shared Mira T. KassoufiD· 2 shared A. Marieke OudelaariD· 1 shared Andrew Smith· 1 shared Barbara XellaiD· 1 shared Benjamin DaviesiD· 1 shared Caroline L. HarroldiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMolecular Biology

Douglas R. HiggsORCID

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2 papers

Recent·Most cited

The characteristics of CTCF binding sequences contribute to enhancer blocking activity

Felice Ho‐Ching Tsang, Rosa J. Stolper, Muhammad Hanifi, Lucy Cornell, Helena S. Francis, Benjamin Davies, Douglas R. Higgs, Mira T. Kassouf

This study identifies CTCF binding sequences that effectively block enhancer-promoter activity, showing that their function is not correlated with CTCF/cohesin levels, conservation, or sequence similarity to consensus motifs.

Nucleic Acids Research · Jul 22, 2024Peer-reviewedMolecular Biology

Multipartite super-enhancers function in an orientation-dependent manner

Mira T. Kassouf, Helena S. Francis, Matthew E. Gosden, Maria Suciu, Damien J. Downes, Caroline L. Harrold, Martin Larke, A. Marieke Oudelaar, Lucy Cornell, Joseph Blayney, Jelena M. Telenius, Barbara Xella, Yuki Shen, Nikolaos Sousos, Jacqueline A. Sharpe, , Douglas R. Higgs

The paper shows that super-enhancers function directionally and orientation-dependently, unlike regular enhancers, by analyzing the β-globin super-enhancer.

bioRxiv · Jul 14, 2022 · PreprintMolecular Biology