Xiaorong Pan

This study identifies ANXA7 as a critical adaptor for TIA1-containing RNP retrograde transport in axons, showing that its disruption leads to TIA1 aggregation and neurodegeneration.

The paper identifies actomyosin-II-driven radial contractility as a mechanism protecting central axons from mild mechanical stress and shows its protective role in a traumatic brain injury model.

The paper introduces an Axon-on-a-Chip model to mimic diffuse axonal injury and study its cellular responses under mechanical stress.