BiochemistrybioRxivPreprint
Revealing the unexpected interplay between the Proteasome Activator PA200 and the immunoproteasome
Dušan Živković, Fatme Mourtada, Angélique Sanchez Dafun…·Marie‐Pierre Bousquet
This paper reveals structural and functional differences in PA200 interaction with the immunoproteasome (i20S) compared to the standard proteasome (s20S), showing PA200 enhances i20S activation and regulates its gene expression.