Author

Anna Czarna

Jagiellonian UniversityORCID 0000-0003-1068-0671Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:machine learning (classical)· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

Grzegorz M. PopowicziD· 3 shared Przemysław GrygieriD· 3 shared Filipe MenezesiD· 2 shared Katarzyna PustelnyiD· 2 shared Adam WahidaiD· 1 shared Adrien DelpaliD· 1 shared Agata BarzowskaiD· 1 shared Alex MatsudaiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersBioinformatics

Grzegorz M. PopowiczORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BiochemistryRSC Medicinal ChemistryPeer-reviewedJan 1, 2026

Crystallographic characterisation and development of bi-substrate inhibitors of coronavirus nsp14 methyltransferase

Irene Georgiou, Colin Robinson, Sean N. O’Byrne…·Ian Hugh Gilbert

The paper develops bi-substrate inhibitors of SARS-CoV-2 nsp14 methyltransferase using structure-guided design, achieving nanomolar potency but limited cellular antiviral activity.

2 citations

virusexperimental assay

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BioinformaticsbioRxivPreprintAug 1, 2025

Target Preference Maps: A machine learning model generalizing transferable drug-receptor interactions and guiding drug discovery

Filipe Menezes, Adam Wahida, Tony Fröhlich…·Grzegorz M. Popowicz

The paper introduces a machine learning model that learns spatial preference maps for drug-receptor interactions to guide drug discovery.

DOI 10.1101/2025.08.01.668090

protein structuremachine learning (classical)

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BiochemistrybioRxivPreprintMar 18, 2025

Revealing the unexpected interplay between the Proteasome Activator PA200 and the immunoproteasome

Dušan Živković, Fatme Mourtada, Angélique Sanchez Dafun…·Marie‐Pierre Bousquet

This paper reveals structural and functional differences in PA200 interaction with the immunoproteasome (i20S) compared to the standard proteasome (s20S), showing PA200 enhances i20S activation and regulates its gene expression.

2 citations

structural biologyexperimental assay

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Molecular BiologybioRxivPreprintJun 10, 2024

Curcumin Inhibition of DYRK Kinases

Filipe Menezes, Przemysław Grygier, Katarzyna Pustelny…·Anna Czarna

This paper investigates how curcumin interacts with DYRK1A and DYRK2 kinases, showing its potential to treat diabetes and cancer by modulating these proteins.

DOI 10.1101/2024.06.10.598318

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