PathologybioRxivPreprint
Oral Administration of the carboxylic acid ester prodrug NHC SN_9 protects mice from lethal Orthopoxvirus challenge: Implications for the Treatment of Monkeypox
Andrei E. Siniavin, Vladimir А. Gushchin, Наталья Сергеевна Шастина…·Denis Y. Logunov
This study evaluates the antiviral efficacy of SN_9, a prodrug of NHC, against orthopoxviruses in mice, showing significant survival and reduced disease severity.
DOI 10.64898/2025.12.30.696971