Denis Y. Logunov

scParadise provides tools for accurate cell type annotation and surface protein prediction in scRNA-seq data, improving performance for rare cell types and clustering.

This study evaluates antibiotic susceptibility of K. pneumoniae biofilms and identifies colistin and tigecycline as most effective against biofilm biomass and metabolic activity.

This study compares circular and linear mRNA vectors, finding linear vectors have higher expression levels but equal immunogenicity and protective activity.

This study evaluates the antiviral efficacy of SN_9, a prodrug of NHC, against orthopoxviruses in mice, showing significant survival and reduced disease severity.

This study compares three TBEV vaccine candidates—mRNA-LNP, recombinant adenovirus, and YFV chimera—and finds the mRNA-LNP vaccine has higher immunogenicity and protective efficacy in mice.

The paper assesses seroprevalence and cross-reactivity of neutralizing antibodies to six adenovirus types and suggests Ad1 or Ad2 as potential vaccine vector candidates.

This study evaluates mRNA-LNP vaccines encoding SARS-CoV-2 structural proteins, finding that the S protein enhances immune responses to N protein, while M protein has low immunogenicity.

This study develops a trivalent mRNA vaccine candidate for seasonal flu, showing higher immunogenicity and cross-specific humoral immune response compared to an inactivated split vaccine.

This paper develops an mRNA platform for delivering single-domain antibodies, achieving 100% protection against high doses of botulinum neurotoxin A in mice.