Author
Federal State Budget Institution “National Research Centre for Epidemiology and Microbiology Named after Honorary Academician N. F. Gamaleya” of the Ministry of Health of the Russian Federation, Moscow 123098, RussiaORCID 0000-0001-7576-2059Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Andrei E. Siniavin, Vladimir А. Gushchin, Наталья Сергеевна Шастина…·Denis Y. Logunov
This study evaluates the antiviral efficacy of SN_9, a prodrug of NHC, against orthopoxviruses in mice, showing significant survival and reduced disease severity.
Andrei E. Siniavin, Anna A. Iliukhina, Daria M. Grousova…·Vladimir А. Gushchin
This study establishes an IFN-deficient mouse model for CCHFV infection to evaluate pathogenicity and vaccine efficacy.
Nadezhda A. Kuznetsova, Vladimir А. Gushchin, Elizaveta V. Marchuk…·Alexander L. Gintsburg
This study compares three TBEV vaccine candidates—mRNA-LNP, recombinant adenovirus, and YFV chimera—and finds the mRNA-LNP vaccine has higher immunogenicity and protective efficacy in mice.
Evgeniia N. Bykonia, Denis A. Kleymenov, Vladimir A. Gushchin…·Alexander L. Gintsburg
This study evaluates mRNA-LNP vaccines encoding SARS-CoV-2 structural proteins, finding that the S protein enhances immune responses to N protein, while M protein has low immunogenicity.
Elena P. Mazunina, Vladimir A. Gushchin, Denis A. Kleymenov…·Alexander L. Gintsburg
This study develops a trivalent mRNA vaccine candidate for seasonal flu, showing higher immunogenicity and cross-specific humoral immune response compared to an inactivated split vaccine.
A. E. Siniavin, I. V. Dolzhikova, A. A. Pochtovyi…·V. A. Gushchin
This study evaluates the lethality of different West Nile virus strains in a mouse model, highlighting the impact of amino acid substitutions on pathogenesis and vaccine development.