Author

Christina Savva

Karolinska InstitutetORCID 0000-0002-8019-1104Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Organism:human· 1

Frequent Co-Authors

Alexander SchmidtiD· 1 shared Amena ArcheriD· 1 shared Amir Ata SaeiiD· 1 shared Carl PeterssoniD· 1 shared Carlos J. Gallardo-DoddiD· 1 shared Cecilia WilliamsiD· 1 shared Cholsoon JangiD· 1 shared Christian SommeraueriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSystems Biology

Alexander SchmidtORCID

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2 papers

Recent·Most cited

A systemic circadian nicotinic acid riboside (NaR) signal engages the unfolded protein response and adipogenesis via the prefoldin complex

Ivan Vlassakev, Christina Savva, Liying Zhou, Danilo Ritz, Alexander Schmidt, Cholsoon Jang, Amir Ata Saei, Paul Petrus

This paper identifies NaR as a liver clock-controlled metabolite that links circadian rhythms to adipogenesis via the prefoldin complex and UPR signaling.

bioRxiv · Mar 6, 2026 · PreprintSystems Biology

Estrogen receptor activation remodels TEAD1 gene expression to alleviate nonalcoholic fatty liver disease

Christian Sommerauer, Carlos J. Gallardo-Dodd, Christina Savva, Linnea Hases, Madeleine Birgersson, Rajitha Indukuri, Joanne X. Shen, Pablo Carravilla, Keyi Geng, Jonas Nørskov Søndergaard, Clàudia Ferrer-Aumatell, Grégoire Mercier, Erdinç Sezgin, Marion Korach-André, Carl Petersson, , Claudia Kutter

This study shows that activating estrogen receptors in male mice reduces HFD-induced liver steatosis by modulating gene expression and TEAD1, suggesting TEAD1 inhibition as a therapeutic strategy for NAFLD.

Molecular Systems Biology · Mar 8, 2024Peer-reviewedGenomics