Hitoshi Takizawa

This study tracks Gfi1 expression dynamics during hematopoietic development and identifies its role in defining EHT and HSC potency.

The paper identifies G-CSF produced by skin endothelial cells as a driver of pathological granulopoiesis and neutrophil infiltration in psoriasis, offering a potential therapeutic target.

The paper shows that IL-1 signaling suppresses Wnt activity in epidermal stem cells during inflammation, leading to changes in stem cell compartments that can be reversed by Wnt reactivation.

This study identifies Plcl1 as a regulator of calcium dynamics in hematopoietic stem cells, affecting their function during aging and stress.

The paper identifies TCF7L2 as a gene associated with antidepressant effects on hippocampal astrocytes in depression model mice.

This paper demonstrates the use of X-ray-induced scintillation to remotely control neural function in mice, achieving bidirectional modulation of behavior through optogenetic activation and inhibition.